Name: 5 Amino 1MQ 50mg (Research Peptide)
Brand: Verum Peptides
Price: 79 USD
Availability: InStock

Identification

Chemical name	5-amino-1-methylquinolinium iodide
Common designation	5-Amino-1MQ; 5A1MQ; NNMTi
Compound class	Small-molecule quaternary quinolinium. Not a peptide; no amino acid sequence applies.
Molecular formula	C10H11IN2 as supplied · C10H11N2+ cation
Molecular weight	286.11 g/mol as supplied · 159.21 g/mol for the cation
CAS number	42464-96-0
Molecular target	Nicotinamide N-methyltransferase, substrate-competitive. Reported IC50 1.2 µM under the assay conditions described in the founding literature.
Physical form	Orange lyophilized powder
Solubility	Water; dimethyl sulfoxide
Quantity supplied	50 mg nominal per unit, as the iodide salt
Country of manufacture	United States

Note on the quantity basis

This compound is a quaternary cation and is supplied as a salt. The iodide salt has a molecular weight of 286.11 g/mol; the cation alone is 159.21 g/mol. Approximately 1.89 mg of the salt therefore corresponds to 1 mg of the cation.

The quantity stated on this listing is the mass of the iodide salt. Molarity calculations should use 286.11 rather than 159.21. A listing elsewhere stating a quantity without identifying the basis is not specifying which figure is meant.

Certificate of analysis - current lot

The interactive verification record for this product is shown below, followed by the same information reproduced as text on this page and the full certificate as a document. The record does not depend on the embed loading.

Certificate of analysis - lot JRZTDB

Lot record

JRZTDB

Testing laboratory	Freedom Diagnostics, United States
Laboratory relationship	Independent third party. Not owned by, affiliated with, or operated by Verum.
Sample received	11 May 2026
Results reported	12 May 2026
Accession reference	2605110195
Analytical method	High-performance liquid chromatography with ultraviolet detection coupled to mass spectrometry (HPLC-UV / LC-MS)

Results, this lot

Identity, LC-MS	Confirmed as 5-Amino-1MQ
Purity, HPLC-UV	99.94 %
Net content	59.17 mg per unit
Appearance	Orange lyophilized powder
Mass confirmation	Principal ion observed at m/z 159, consistent with the quinolinium cation

Purity and content figures above are specific to lot JRZTDB and are not a specification carried across other lots. Each lot is tested individually and reports its own results. The certificate supplied with your unit records the results for that lot.

Testing scope

Panels differ between products and between lots. What follows is the scope of testing performed on this lot. Nothing is claimed unless it appears on the certificate for the lot supplied.

Performed

✓	Identity by LC-MS
✓	Purity by HPLC-UV
✓	Net content by mass
✓	Appearance by visual inspection
✓	Mass confirmation

Not performed

-	Bacterial endotoxin
-	Sterility
-	Microbial enumeration
-	Elemental impurities
-	Residual solvents
-	Water content

Where a parameter is material to intended laboratory work, purchasers should verify it independently or source material released against that specification.

Storage and laboratory handling

Powder, transit	Stable at ambient temperature during shipping and short-term handling. Cold-chain transport is not required.
Powder, storage	−20 °C, protected from light, container tightly closed
Solubility	Water; dimethyl sulfoxide. Select the solvent appropriate to the assay.
Solution, storage	2 °C to 8 °C, protected from light
Freeze-thaw	Avoid repeated cycles. Aliquot at first preparation where the protocol allows.
Compound-specific note	Quaternary ammonium salts are hygroscopic. Allow the container to reach room temperature before opening, or condensation will be drawn into the powder. Reseal promptly.
Personal protection	Handle under standard laboratory conditions with gloves, eye protection and a laboratory coat.

Preparation conditions are the responsibility of the receiving laboratory. Verum provides no protocol, no preparation instruction, and no guidance on use.

Published literature

References are listed for bibliographic purposes and are indexed by the experimental system used. Each description states what the study measured, not what it concluded. Every entry was conducted in cultured cells or in rodents. No clinical study of this compound has been published. Verum has no involvement in any of this work and makes no representation as to its applicability.

Cell culture
& rodent

2018

Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase

Neelakantan H, Vance V, Wetzel MD, et al. · Biochemical Pharmacology

Measured enzyme inhibition and selectivity against related methyltransferases, then intracellular 1-methylnicotinamide, NAD+ and S-adenosylmethionine levels in cultured adipocytes. Extended to body composition and adipocyte size in a rodent model. The founding characterisation of this compound.

PubMed 29155147 →

Rodent

2022

Reduced calorie diet combined with NNMT inhibition establishes a distinct microbiome

Dimet-Wiley A, Wu Q, Wiley JT, et al. · Scientific Reports

Sequenced gut microbial composition alongside body composition in a rodent model receiving enzyme inhibition with and without caloric restriction. Relevant as a design reference for separating compound effects from dietary effects.

PubMed 35013352 →

Aged rodent

2024

NNMT inhibition and exercise-mediated changes in skeletal muscle function in aged mice

Dimet-Wiley AL, et al. · Scientific Reports

Measured grip strength and skeletal muscle endpoints in 24-month-old animals, with and without an exercise intervention, to test whether the two act through overlapping or separate routes. The only entry working outside adipose tissue.

PubMed 38969654 →

No clinical study of this compound has been published and the consequences of inhibiting this enzyme over extended periods are not established.

Regulatory status

United States	Not approved by the FDA for any indication. Not on the section 503A bulk drug substances list.
Other jurisdictions	No marketing authorisation is held in any jurisdiction.
Status date	Accurate as of August 2026. Verify the current position independently.

Purchase eligibility

By placing an order you confirm each of the following:

✓	You are at least 21 years of age.
✓	You are a qualified researcher, or are purchasing on behalf of a research institution or commercial laboratory.
✓	The material will be used solely for in vitro laboratory research.
✓	The material will not be administered to humans or to animals, and will not be resold or transferred for any such purpose.
✓	You are responsible for compliance with all federal, state and local law governing receipt, handling, storage and use.

Confirmation is recorded at checkout against your order. Verum reserves the right to decline or cancel any order.

Supply

Orders placed before the daily cutoff are dispatched the same day from our United States warehouse. Domestic orders typically arrive within two business days. A tracking reference is issued by email once the consignment leaves the facility. Each unit carries a scannable code linking to the certificate for its own lot.

Not for human or veterinary use. Not for use in diagnostic or therapeutic procedures. This product is a laboratory reagent. Nothing on this page constitutes medical advice, a recommendation for personal use, or a representation that this material is safe or effective for any purpose. No statement here has been evaluated by the U.S. Food and Drug Administration.