GHK-Cu

Note on the quantity basis

A milligram figure on a coordination complex is ambiguous unless the basis is stated. The ligand is 340.4 g/mol and the complex is 401.9 g/mol, so the peptide accounts for roughly eighty-five percent of the complex by mass and the copper with its coordination for the remaining fifteen.

100 mg of the complex therefore contains approximately 85 mg of the GHK ligand. Read the content figure on the certificate for your lot, and where the basis is not stated, establish it before calculating a molarity. A fifteen percent difference in a stock concentration is not a rounding matter.

02

Each size is tested and released separately and carries its own certificate. Both are set out below: the interactive verification record, the certificate document, and the same information reproduced as text on this page. The record does not depend on the embeds loading. The panels differ between the two current lots, which is why they are presented separately rather than combined.

50 mg

Certificate of analysis - lot 8ZVN1B, 50 mg

Lot record - 50 mg

8ZVN1B

Results, lot 8ZVN1B

100 mg

Certificate of analysis - lot GHK100-052026-4, 100 mg

Lot record - 100 mg

GHK100-052026-4

Results, lot GHK100-052026-4

Purity and content figures above are specific to the lots named and are not specifications carried across other lots. The two current lots differ in both content and panel scope, which is precisely why this catalogue states results per lot rather than per product. The certificate supplied with your unit records the results for that lot.

03

Chromatography with ultraviolet detection measures the peptide. Mass spectrometry under electrospray conditions frequently strips the metal from a labile coordination complex in the ion source, so the ion appearing on the trace is commonly the free ligand near 341 rather than the intact complex near 403.

That is what both certificates above show, and it is ordinary instrument behaviour rather than a defect in the material. It has a consequence that is routinely glossed over: a mass confirmation on this compound establishes that the ligand is GHK. On its own it does not establish how much copper is present, or that the stoichiometry is correct.

Establishing copper content requires an elemental method, inductively coupled plasma spectrometry or equivalent. That is not part of a standard peptide panel and is not on either certificate above. Where a supplier states that mass spectrometry confirms the copper complex, the question to ask is which ion was observed.

What is available is simpler. The intense blue of this material arises from d-orbital transitions in coordinated copper(II), and a preparation of the same ligand without copper is white. Elsewhere in this catalogue we note that cake appearance establishes very little. On this compound it is the most direct indication of coordinated copper available, and it appears on the certificate as a recorded observation rather than as a description supplied by us.

04

Panels differ between products, between sizes and between lots. The columns below reflect the two current lots. Nothing is claimed unless it appears on the certificate for the lot supplied.

The first entry in the right-hand column is the one that matters on this compound; see the section above. Where a parameter is material to intended laboratory work, purchasers should verify it independently or source material released against that specification.

05

Preparation conditions are the responsibility of the receiving laboratory. Verum provides no protocol, no preparation instruction, and no guidance on use.

06

The two units contain the same material and differ in fill. The larger is not automatically the better value on a coordination complex: once in solution, copper speciation is the variable governing how the material behaves, and a solution held longer has more opportunity to change. Select the fill that matches what will be consumed. Note also that the two sizes are released against separate certificates with different panels, so the applicable testing scope depends on which is ordered.

07

08

By placing an order you confirm each of the following:

Confirmation is recorded at checkout against your order. Verum reserves the right to decline or cancel any order.

09

Orders placed before the daily cutoff are dispatched the same day from our United States warehouse. Domestic orders typically arrive within two business days. A tracking reference is issued by email once the consignment leaves the facility. Each unit carries a scannable code linking to the certificate for its own lot.

Not for human or veterinary use. Not for use in diagnostic or therapeutic procedures. This product is a laboratory reagent and is not a cosmetic ingredient as supplied. Nothing on this page constitutes medical advice, a recommendation for personal use, or a representation that this material is safe or effective for any purpose. No statement here has been evaluated by the U.S. Food and Drug Administration.