PT-141

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The interactive verification record is shown below, followed by the same information reproduced as text on this page and the full certificate as a document. The record does not depend on the embed loading.

Certificate of analysis - lot YGAFK7

Lot record

YGAFK7

Results, this lot

Purity and content figures above are specific to lot YGAFK7 and are not a specification carried across other lots. Each lot is tested individually and reports its own results.

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These two compounds are far closer than their separate names suggest, and understanding the relationship is the most useful thing on this page.

Melanotan II is an acetylated cyclic heptapeptide closed by a lactam bridge, terminating in a carboxamide. This compound is the same acetylated cyclic heptapeptide, closed by the same lactam bridge, terminating in a free carboxylic acid instead. That single terminal difference is the whole structural distinction, and it is not arbitrary: this compound arises as a metabolite of the amide form, which is how it was identified.

The consequence is a shift in receptor preference rather than a change of family. Both engage multiple melanocortin receptors. The amide form is described in the literature as the more promiscuous of the two, with relatively greater activity at the melanocortin-1 receptor found on melanocytes. The free acid is described as weighted more toward the melanocortin-4 receptor. Weighted more toward is not the same as selective for, and any experimental design treating this compound as an MC4R-only tool without controls for the other subtypes is assuming a cleanliness the pharmacology does not support.

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Two compounds differing only in whether a terminal group is an amide or an acid differ in mass by approximately one dalton. On the free acid the protonated ion sits near 1026 and the doubly protonated ion near 513. The amide form sits one unit lower.

One dalton is a small separation but a real one on a competent instrument, and it is not something a purity percentage or a retention time resolves on its own. This is a case where a certificate publishing the mass confirmation does work that a certificate reporting only a percentage cannot. Look at the ion series on the certificate above before anything else.

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Panels differ between products and between lots. What follows is the scope of testing performed on this lot. Nothing is claimed unless it appears on the certificate for the lot supplied.

Mass spectrometry cannot distinguish a D-amino acid from its L counterpart because they weigh the same. Confirming stereochemistry requires chiral analysis, which is not part of this panel or of any standard peptide panel. Where a parameter is material to intended laboratory work, purchasers should verify it independently.

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Preparation conditions are the responsibility of the receiving laboratory. Verum provides no protocol, no preparation instruction, and no guidance on use.

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This page carries no bibliography. The published record on bremelanotide consists overwhelmingly of registration trials conducted in human participants using an approved pharmaceutical product manufactured to standards this material is not manufactured to, and reproducing those beside a research-labelled unit would misrepresent what is being sold here. Researchers working on melanocortin receptor pharmacology already know where that literature lives.

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By placing an order you confirm each of the following:

Confirmation is recorded at checkout against your order. Verum reserves the right to decline or cancel any order.

Bremelanotide is available in the United States as an approved prescription medicine, and is additionally obtainable through licensed compounding pharmacies on a patient-specific prescription. If either of those is what you are looking for, a licensed prescriber is the correct route and this is not a substitute for it.

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Orders placed before the daily cutoff are dispatched the same day from our United States warehouse. Domestic orders typically arrive within two business days. A tracking reference is issued by email once the consignment leaves the facility. Each unit carries a scannable code linking to the certificate for its own lot.

Not for human or veterinary use. Not for use in diagnostic or therapeutic procedures. This product is a laboratory reagent. Nothing on this page constitutes medical advice, a recommendation for personal use, or a representation that this material is safe or effective for any purpose. No statement here has been evaluated by the U.S. Food and Drug Administration.