Semax

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The interactive verification record is shown below, followed by the same information reproduced as text on this page and the full certificate as a document. The record does not depend on the embed loading.

Certificate of analysis - batch HKUDQ4

Batch record

HKUDQ4

Results, this batch

Figures above are specific to batch HKUDQ4 and are not specifications carried across other batches. Each batch is tested individually and reports its own results.

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This molecule is not a single designed sequence. The first four residues correspond to a fragment of adrenocorticotropic hormone, a well-characterised endogenous peptide. The last three, proline-glycine-proline, are a synthetic extension whose purpose is to slow enzymatic trimming of the natural fragment rather than to create a new pharmacophore.

That construction is worth recognising because it is shared. Our Selank listing is the same idea applied to a different natural core: a four-residue endogenous fragment with the identical proline-glycine-proline tail. The two compounds came out of the same design logic and differ in what sits in front of the extension.

For experimental design the implication is the same on both. Any observation from this material may be attributable to the four-residue core, to the intact heptapeptide, or to fragments generated as the extension is trimmed. Those are three candidate species, and a design that does not include the bare core as a comparator leaves the most obvious alternative explanation untested.

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The certificate above reports 8.30 mg per unit against a 10 mg nominal. That figure is printed here rather than summarised away, and it deserves an explanation rather than a shrug.

A quantity on a peptide unit can mean two different things. Gross fill weight is how much powder went into the container. Peptide content is how much of that powder is the peptide itself. The two are never identical, because a synthesised peptide is isolated as a salt carrying a counterion and because lyophilized material retains residual moisture. On a typical preparation the peptide accounts for roughly seventy to ninety percent of the powder by weight, with the balance being counterion and water. A container filled honestly to its gross target will still measure below that target when the peptide alone is quantified.

In practice: calculate from the measured figure on the certificate for the batch supplied, not from the nominal on the label. Where a protocol depends on a precise quantity that is the only number worth using. A supplier who does not measure content cannot tell you either way, which is the more common situation in this category.

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Several certificates in this catalogue publish a mass confirmation alongside the purity figure. This one does not. The laboratory releasing this batch reports purity and content per unit, and does not print a mass spectrum on the face of the document.

A purity figure describes how much of what eluted was one peak. It does not, on its own, establish the molecular weight of that peak. On a seven-residue sequence built from a four-residue natural core, the species most worth excluding are precisely those a chromatographic method may not separate cleanly: the bare core, and truncations that have lost part of the extension.

There is a second reason it matters here specifically. This sequence carries a methionine, and methionine oxidised to the sulfoxide is sixteen daltons heavier with the same sequence and similar retention. A mass measurement separates those two; a percentage does not. Where molecular weight confirmation is material to your work, request it before ordering or source material released against it. For reference, the intact heptapeptide gives a protonated ion near 815.

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Several short peptides in this catalogue carry no oxidation-sensitive residues at all and are correspondingly forgiving. This one is not among them. The methionine at position 1 oxidises to the sulfoxide, and the product has the correct sequence, a mass sixteen daltons higher, and altered behaviour.

One instruction follows for anyone buying across this catalogue: keep this peptide away from copper. The copper complex sold here, and the blends built around it, are redox-active, and copper together with a methionine-containing sequence accelerates exactly the chemistry above. Do not share buffers, do not combine working solutions, and treat labware that has carried a copper complex as unsuitable for this material. The same applies to free iron and to any oxidising buffer component.

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Panels differ between products and between batches. What follows is the scope of testing performed on this batch. Nothing is claimed unless it appears on the certificate for the batch supplied.

This is among the narrowest panels in the catalogue and it is presented as such. Where a parameter is material to intended laboratory work, purchasers should verify it independently or source material released against that specification.

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Preparation conditions are the responsibility of the receiving laboratory. Verum provides no protocol, no preparation instruction, and no guidance on use.

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This page carries no bibliography. We list references only where we can link them directly, so a reader can check the source rather than take our description of it, and we are not able to do that reliably for this compound. A summary of work we cannot point you to would be an assertion rather than a citation, and we would rather leave the section empty than fill it with one. Researchers should search the primary record themselves.

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By placing an order you confirm each of the following:

Confirmation is recorded at checkout against your order. Verum reserves the right to decline or cancel any order.

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Orders placed before the daily cutoff are dispatched the same day from our United States warehouse. Domestic orders typically arrive within two business days. A tracking reference is issued by email once the consignment leaves the facility. Each unit carries a scannable code linking to the certificate for its own batch.

Not for human or veterinary use. Not for use in diagnostic or therapeutic procedures. This product is a laboratory reagent. Nothing on this page constitutes medical advice, a recommendation for personal use, or a representation that this material is safe or effective for any purpose. No statement here has been evaluated by the U.S. Food and Drug Administration.